Molecular oncology focus - Is carcinogenesis a 'mitochondriopathy'?
نویسندگان
چکیده
منابع مشابه
Renal Fanconi Syndrome Is Caused by a Mistargeting-Based Mitochondriopathy.
We recently reported an autosomal dominant form of renal Fanconi syndrome caused by a missense mutation in the third codon of the peroxisomal protein EHHADH. The mutation mistargets EHHADH to mitochondria, thereby impairing mitochondrial energy production and, consequently, reabsorption of electrolytes and low-molecular-weight nutrients in the proximal tubule. Here, we further elucidate the mol...
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ژورنال
عنوان ژورنال: Journal of Biomedical Science
سال: 2010
ISSN: 1423-0127
DOI: 10.1186/1423-0127-17-31